Fraxel





In vivo Sunscreen Testing

In vivo sunscreen testing involves photo-testing human subjects after application of the sunscreen at an internationally agreed thickness of 2 mg/cm2 body surface. A “water-resistant” claim can be made for a sunscreen if the SPF is maintained after two 20-minute water immersions. The protection offered by a “water-resistant” sunscreen is indicated by the SPF, which is assessed after photo-testing in vivo. Remember, this SPF rating refers only to protection against UV-B radiation. Sunscreens that do not meet the above criteria following water immersion are not considered “water-resistant”.

Several studies indicate that under in real-world conditions application thickness more likely approximates 0.5-1.0 mg/cm2, lowering the effective SPF of the product. When in vivo SPF testing is conducted outdoors, the efficacy of products is found to be lower than in the laboratory.

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Sunlight & UV rays
SPF Rating
Sunscreen Testing
Critical Wavelength
Sunscreen Ingredients
Photostability
Skin Sensitivity

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